- Published scientific evidence has demonstrated the most common problem preventing normal ovarian follicle function and ovulation in women with POI is inappropriate luteinization of growing follicles.
- Published evidence has demonstrated the NIH P-HRT regimen suppresses serum LH levels to normal in women with POI. Published evidence has demonstrated you should be on the NIH P-HRT regimen to keep your bones healthy.
- Theoretically, lowering the LH level in your blood should improve the chances of you ovulating by reducing the chances of the follicles becoming luteinized. This has not yet been proven by prospective study, however. As a group, women with POI should be advocating for more studies about how to improve their natural fertility.