Discovery of a Rare Genotype Causing Primary Ovarian Insufficiency
Scientists at deCODE genetics and collaborators, have identified a sequence variant in the CCDC201 gene that when inherited from both parents homozygous causes menopause on average nine years earlier...
Breast Cancer Is Increased in Women With Primary Ovarian Insufficiency
Primary ovarian insufficiency (POI) is defined as primary hypogonadism in women before the age of 40 years. Autoimmune causes, FMR1 premutations, and X chromosome deletions and translocations account...
Metabolic Profiling in Plasma and Brain Induced by 17β-Estradiol Supplementation in Ovariectomized Mice
Estrogen deficiency is common in women during menopause and is associated with conditions such as osteoporosis, metabolic dysfunction, and neurological diseases. 17β-Estradiol, one of the primary es...
