Premature Menopause May Increase Risk of Death from Heart Disease, Cancer
Researchers report that women who enter menopause before age 40 are twice as likely to die from heart disease and four times as likely to die from cancer. Experts say hormone replacement therapy ...
The Association Between Primary Ovarian Insufficiency and Increased Multimorbidity
The purpose of this study was to determine the association between age of menopause and multimorbidity in a large Canadian prospective cohort. It was hypothesized that participants with earlier age a...
Discovery of a Rare Genotype Causing Primary Ovarian Insufficiency
Scientists at deCODE genetics and collaborators, have identified a sequence variant in the CCDC201 gene that when inherited from both parents homozygous causes menopause on average nine years earlier...
Breast Cancer Is Increased in Women With Primary Ovarian Insufficiency
Primary ovarian insufficiency (POI) is defined as primary hypogonadism in women before the age of 40 years. Autoimmune causes, FMR1 premutations, and X chromosome deletions and translocations account...
Metabolic Profiling in Plasma and Brain Induced by 17β-Estradiol Supplementation in Ovariectomized Mice
Estrogen deficiency is common in women during menopause and is associated with conditions such as osteoporosis, metabolic dysfunction, and neurological diseases. 17β-Estradiol, one of the primary es...
