
Jane Goodall, a Messenger of Hope
On October 1, 2025, the world said goodbye to Jane Goodall. For decades she inspired millions not only through her groundbreaking work with chimpanzees but also through her message of hope: that small, intentional actions can change the world.
This spirit of hope and intentional action resonates deeply with the Primary Ovarian Insufficiency (POI) Readiness Initiative™. Women facing POI often feel isolated, dismissed, or overwhelmed by fragmented care. What they need is not only medical support but also a structured, empowering approach to change.
A Scientific Framework: Theory of Change
At the same time, researchers are advancing new tools to help health programs grow more effectively. A 2025 article in Implementation Science introduced the SELECT-IT meta-framework for Theory of Change (ToC), which emphasizes:
- Involving stakeholders from the beginning
- Mapping clear pathways from action to outcome
- Testing and refining strategies with real-world evidence
This framework shows how change doesn’t happen by chance—it happens through careful design, collaboration, and feedback loops.
Science Meets Soul: ToC in Action for POI
The POI Readiness Initiative™ is taking these lessons to heart. Our three pillars—education, readiness, and growth mindset—are rooted in ToC principles. For each woman:
- Identify her starting point (fragmented care, lack of HRT, emotional stress).
- Map a path to readiness (collect her health story, prepare referral letters, connect her to the right clinician).
- Test and refine (use feedback from patients and clinicians to improve tools). Like Goodall’s belief that small acts create ripples of change, ToC helps ensure each woman’s step connects to larger outcomes, ToC helps us ensure each step—each checklist, each letter, each conversation—connects to larger goals of empowerment and better outcomes.
What This Means for You
For an individual woman with POI, this means:
- Your voice is central. You’re not a passive recipient of care—you’re a co-designer of your pathway forward.
- Every small step counts. Even documenting symptoms or asking one clear question at a doctor’s visit can shift your trajectory.
- You are part of something bigger. Your journey contributes to building a global model of care and support.
Building Together a Stronger Model
Like Jane Goodall’s legacy, this work requires patience, intention, and hope. With the Theory of Change as our guide and the strength of women’s voices at the center, we can design a system of care that is not only scientifically sound but also emotionally sustaining.
Every woman’s story becomes part of the blueprint. Each experience shared, each small improvement tested, contributes to a model that will serve not just individuals, but generations to come.
Together, we can create a future where women with POI are prepared, supported, and empowered—ready not only to navigate their health but also to shape the very systems that serve them.
Let’s grow forward, together.

Visit My28Days.org to learn more, share your story, and join us in shaping the future of POI care.